Clinical research is written in two languages — medicine and statistics — and almost no author is fluent in both. RigorMD is the second reader that is: a severity-scored methods-and-statistics read of your manuscript, before you submit it.
Built by a practicing academic surgeon and surgical journal editor with 61 peer-reviewed publications and 100+ editorial manuscript reviews. The founder's background also includes large clinical-dataset analysis and statistical modeling for clinical research.
The product reflects that mix of clinical, editorial, research, and statistical-methods work, plus years spent on both sides of peer review. It is purpose-built on research-on-research literature, statistical standards, and the reporting guidelines journals actually enforce.
Too much published clinical research fails methodological scrutiny only after it is in print, and the expertise that would catch problems earlier is scarce, gated, and unevenly distributed. A flawed statistic becomes flawed care. RigorMD exists to close that gap — and to make submitting less stressful: the toughest read your manuscript will ever get happens while it is still yours to fix.
RigorMD is an adjudication system rather than a single AI opinion: two independent LLM engines appraise the manuscript blind, their findings are reconciled, and a deterministic layer recomputes statistics where the reported numbers allow — so a flag is a calculation you can check. Serious and critical findings are adversarially verified before they reach you, and every finding is grounded in your own text and severity-scored across seven domains — the seventh positions the manuscript against prior work retrieved from the medical literature. Every report is version-stamped. Scoring adapts GRADE and the RoB 2 / ROBINS-I risk-of-bias frameworks for pre-submission methodological review; the primary conclusion gets a plain claim–evidence calibration — the signed gap between the confidence the authors state and the support the reported results give it, which rewards a humble read and flags overreach.
A report is guidance based on the submitted materials — it is not a guarantee of journal acceptance, a substitute for peer review, or medical advice. Decisions about your manuscript, and about patient care, remain yours.
Or review pricing — the pre-submission review is $30.